Total synthesis of (±)-tricyclohexaprenol, a possible forerunner of sterols in the evolution of biomembranes

✍ Scribed by E.J. Corey; Robert M. Burk

• Book ID: 104228169
• Publisher: Elsevier Science
• Year: 1987
• Tongue: French
• Weight: 262 KB
• Volume: 28
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)96875-8

✦ Synopsis

f)-Tricyclohexaprenol (1) has been synthesized by a route involving concurrent generation of the three rings by Hg(II)-promoted conversion of 3 to 4, and subsequent attachment of a C,O, E,E-diene unit using the allylic silane 10, prepared from geraniol. Tricyclohexaprenol(1)