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Total synthesis of (.+-.)-thienamycin

โœ Scribed by Johnston, David B. R.; Schmitt, Susan M.; Bouffard, F. Aileen; Christensen, B. G.


Book ID
125995927
Publisher
American Chemical Society
Year
1978
Tongue
English
Weight
406 KB
Volume
100
Category
Article
ISSN
0002-7863

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Total synthesis of thienamycin analogs.
โœ L. Cama; B.G. Christensen ๐Ÿ“‚ Article ๐Ÿ“… 1980 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 225 KB

## Jersey 07065 A new general synthesis leading to 24kyl and 2-aryl-l-carba-2-penem-3-carboxylic acids involves the preparation of a key thiolester intermediate 3. This is reacted with Me CuLi or (C6H5)2MgCuX to give the correspond@ methyl or phenyl ketone which undergoes a Wittig rea A\* mn to gi