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Total Synthesis of the Tropoloisoquinoline Alkaloid Pareitropone via Alkynyliodonium Salt Chemistry and Related Studies

✍ Scribed by Feldman, Ken S.; Cutarelli, Timothy D.; Di Florio, Romina


Book ID
126436138
Publisher
American Chemical Society
Year
2002
Tongue
English
Weight
235 KB
Volume
67
Category
Article
ISSN
0022-3263

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General approach for the total synthesis
✍ Jianming Yu; Xiangyu Z Wearing; James M Cook πŸ“‚ Article πŸ“… 2003 πŸ› Elsevier Science 🌐 French βš– 136 KB

The stereospecific total synthesis of (+)-N a -methyl-16-epipericyclivine (1) was completed [from D-(+)-tryptophan methyl ester] in an overall yield of 42% (eight reaction vessels). The optical rotation {[h] D +22.8 (c 0.50, CHCl 3 )} obtained on this material confirmed that the reported optical rot