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Total Synthesis of the Triglycosyl Phenolic Glycolipid PGL-tb1 from Mycobacterium tuberculosis

✍ Scribed by Barroso, Santiago; Castelli, Riccardo; Baggelaar, Marc P.; Geerdink, Danny; ter Horst, Bjorn; Casas-Arce, Eva; Overkleeft, Herman S.; van der Marel, Gijsbert A.; Codée, Jeroen D. C.; Minnaard, Adriaan J.


Book ID
118752194
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
441 KB
Volume
51
Category
Article
ISSN
0044-8249

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Chemical synthesis of the trisaccharide
✍ Tsuyoshi Fujiwara; Gerald O. Aspinall; Shirley W. Hunter; Patrick J. Brennan 📂 Article 📅 1987 🏛 Elsevier Science 🌐 English ⚖ 838 KB

O-(3,6-Di-O-methyl-beta-D-glucopyranosyl)-(1----4)-O-(2,3-di-O-methyl- alpha-L-rhamnopyranosyl)-(1----2)-3-O-methyl-L-rhamnopyranose, the haptenic trisaccharide of the Mycobacterium leprae-specific phenolic glycolipid I (PGL-I) antigen, and related trisaccharides, were synthesized by allylation of O