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Total Synthesis of the Teicoplanin Aglycon

✍ Scribed by Boger, Dale L.; Kim, Seong Heon; Miyazaki, Susumu; Strittmatter, Harald; Weng, Jian-Hui; Mori, Yoshiki; Rogel, Olivier; Castle, Steven L.; McAtee, J. Jeffrey

Book ID: 126810943
Publisher: American Chemical Society
Year: 2000
Tongue: English
Weight: 60 KB
Volume: 122
Category: Article
ISSN: 0002-7863
DOI: 10.1021/ja001663j

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The callipeltosides were isolated by Minale and co-workers from the shallow-water lithistid sponge Callipelta sp., collected off the east coast of New Caledonia. [1a,b] Callipeltoside A (1 in Scheme 1, obtained in 1.4 Â 10 À4 % yield) was found to inhibit in vitro the proliferation of KB and P388 ce