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Total Synthesis of the Opioid Agonistic Indole Alkaloid Mitragynine and the First Total Syntheses of 9-Methoxygeissoschizol and 9-Methoxy- N b -methylgeissoschizol

✍ Scribed by Ma, Jun; Yin, Wenyuan; Zhou, Hao; Cook, James M.


Book ID
120351247
Publisher
American Chemical Society
Year
2007
Tongue
English
Weight
92 KB
Volume
9
Category
Article
ISSN
1523-7060

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Ξ²-Carboline alkaloids 9 [1]. Total synth
✍ Franz Bracher; Andreas Puzik πŸ“‚ Article πŸ“… 2004 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 128 KB πŸ‘ 1 views

## Abstract The first total synthesis of the β‐carboline alkaloids arenarine A **(1)** and arenarine B **(2)** is described. Methanolysis of the α‐bromoketone **9** gives **1** in good yield. Alternatively **1** can be obtained from the diazoketone **11** with boron trifluoride/methanol in poor yie