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Total Synthesis of Terprenin, a Highly Potent and Novel Immunoglobulin E Antibody Suppressant

✍ Scribed by Kenji Kawada; Akinori Arimura; Tatsuo Tsuri; Masahiro Fuji; Tadafumi Komurasaki; Shuji Yonezawa; Akira Kugimiya; Nobuhiro Haga; Susumu Mitsumori; Masanao Inagaki; Takuji Nakatani; Yoshinori Tamura; Shozo Takechi; Teruhiko Taishi; Junji Kishino; Mitsuaki Ohtani

Publisher: John Wiley and Sons
Year: 1998
Tongue: English
Weight: 89 KB
Volume: 37
Category: Article
ISSN: 0044-8249
DOI: 10.1002/(sici)1521-3773(19980420)37:7<973::aid-anie973>3.0.co;2-t

No coin nor oath required. For personal study only.

✦ Synopsis

Regioselective halogenations and Suzuki reactions ensure proper linkage of the aromatic rings in two total syntheses of terprenin (1). Both routes make it possible to prepare 1 efficiently and in large quantity.

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