ChemInform Abstract: Total Synthesis of
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Daniel Sole; Josep Bonjoch; Silvina Garcia-Rubio; Emma Peidro; Joan Bosch
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Article
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2010
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John Wiley and Sons
⚖ 35 KB
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Total Synthesis of (-)-Strychnine via the Wieland-Gumlich Aldehyde. -A novel synthesis of optically pure (-)-strychnine (XI) is presented involving the easy generation of enantiopure octahydroindolone (III), the palladium-catalyzed piperidine ring closure with stereoselective incorporation of the E-