General Approach to Anthrapyran Antibiot
✍
Karsten Krohn; Hoan Trang Tran-Thien; Ishtiaq Ahmed
📂
Article
📅
2011
🏛
John Wiley and Sons
🌐
English
⚖ 129 KB
## Abstract A new general route to the anthrapyran antibiotics is presented, which allows the attachment of various branched side chains. A key step is the Baker–Venkataraman rearrangement of the propionate **9** to the diketone **10**. Acid‐catalyzed cyclization gives the ethyl‐branched anthrapyra