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Total synthesis of prostaglandins F1.alpha., E1, F2.alpha., and E2 (natural forms) from a common synthetic intermediate

โœ Scribed by Corey, Elias J.; Noyori, Ryozi.; Schaaf, Thomas K.


Book ID
120870519
Publisher
American Chemical Society
Year
1970
Tongue
English
Weight
288 KB
Volume
92
Category
Article
ISSN
0002-7863

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The function and sites of action of prostaglandins (PGs) vary in different animal species and tissues. In this study the influence of PGs (El, E2, F2,~p~a, D2) on muscle tone and nerve-mediated contraction was investigated in isolated bovine iris sphincter muscles. None of these PGs exogenously app