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Total Synthesis of (±)-Pentalenene via small ring intermediates

✍ Scribed by Michel Miesch; Laurence Miesch-Gross; Michel Franck-Neumann


Book ID
108374556
Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
480 KB
Volume
53
Category
Article
ISSN
0040-4020

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Synthesis of the angular triquinane (±)-
✍ Michel Franck-Neumann; Michel Miesch; Laurence Gross 📂 Article 📅 1992 🏛 Elsevier Science 🌐 French ⚖ 266 KB

Dimethyl t-butylsilyl enol ethers of cycloalkananes react with ethyl propynoore in the presence of ZrCl4 to give protected cyclobutenic hydroxy esters. Cycloproponation by cycloaddition of diazoalkanes followed by sensitized photocleavage. leads to bicycle I2.1 .O] pentan-2-ol derivatives which are