## Abstract A stereoselective four‐step synthesis of racemic patchouli alcohol starting from the known 2,6,6‐trimethyl‐2,4‐cyclohexadien‐1‐one [1] and 3‐methylpent‐4‐en‐1‐ol [2] is described.
Total synthesis of (±)-patchouli alcohol and (±)-seychellene via a common homoisotwistane intermediate
✍ Scribed by K. Yamada; Y. Kyotani; S. Manabe; M. Suzuki
- Publisher
- Elsevier Science
- Year
- 1979
- Tongue
- French
- Weight
- 582 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0040-4020
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## Abstract An efficient, general synthetic route to the bengamide family of antitumor agents from a common polyol thioester is described. Consecutive aldol condensations afford the protected polyol thioester side chain suitable for coupling to the bengamides. A novel chiral‐phase‐transfer‐catalyze
U r a c i l , 6,7-dimethyllumazine, and lumichrome have been l a b e l l e d w i t h carbon-13 a t p o s i t i o n s 6 , 8a, and 10a, respect i v e l y . This w a s accomplished v i a a common i n t e r m e d i a t e , ~y a n o a c e t y l u r e a -6 -~~C . Lumazine and lumichrome w e r e condens a