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Total synthesis of NPTX-5 and NPTX-6, Joro spider (Nephila clavata) toxins having a unique putreanine trimer and putreanine tetramer acylpolyamine chain

✍ Scribed by Hiroaki Saito; Etsuko Yuri; Masahiro Miyazawa; Yasuhiro Itagaki; Terumi Nakajima; Masaaki Miyashita

Publisher: Elsevier Science
Year: 1998
Tongue: French
Weight: 220 KB
Volume: 39
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(98)01379-3

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✦ Synopsis

The first total synthesis of NPTX-5 and NPTX-6, Joro spider (Nephila clavata) toxins having a 4-hydroxyindole nucleus and a unique putreanine trimer and tetramer acylpolyamine chain, respectively, has been achieved by the iterative use of a key azide compound.

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ChemInform Abstract: Total Synthesis of NPTX-5 and NPTX-6, Joro Spider (Nephila clavata) Toxins Having a Unique Putreanine Trimer and Putreanine Tetramer Acylpolyamine Chain.

✍ H. SAITO; E. YURI; M. MIYAZAWA; Y. ITAGAKI; T. NAKAJIMA; M. MIYASHITA 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 29 KB 👁 2 views

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ChemInform Abstract: Total Synthesis of Nephilatoxin-1 (NPTX-1), a Joro Spider (Nephila clavata) Toxin Having a 4-Hydroxyindole Nucleus.

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