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Total Synthesis of Murrayanine Involving 4,5-Dimethyleneoxazolidin-2-ones and a Palladium(0)-Catalyzed Diaryl Insertion.

✍ Scribed by Pablo Bernal; Joaquin Tamariz


Publisher
John Wiley and Sons
Year
2007
Weight
20 KB
Volume
38
Category
Article
ISSN
0931-7597

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Abstract

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Total Synthesis of Murrayanine Involving
✍ Pablo Bernal; JoaquΓ­n Tamariz πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 German βš– 80 KB

## Abstract A new total synthesis of the natural carbazole murrayanine (**1**) was developed by using the 4,5‐dimethyleneoxazolidin‐2‐one **12** as starting material. The latter underwent a highly regioselective __Diels–Alder__ cycloaddition with acrylaldehyde (=prop‐2‐enal; **13**) to give adduct