Total Synthesis of Maoecrystal V: Early-Stage C–H Functionalization and Lactone Assembly by Radical Cyclization

ChemInform Abstract: Total Synthesis of

ChemInform Abstract: Total Synthesis of seco-(+)- and ent-(-)-Oxaduocarmycin SA: Construction of the (Chloromethyl)indoline Alkylating Subunit by a Novel Intramolecular Aryl Radical Cyclization onto a Vinyl Chloride.

✍ V. F. PATEL; S. L. ANDIS; J. K. ENKEMA; D. A. JOHNSON; J. H. KENNEDY; F. MOHAMAD 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 39 KB 👁 2 views

Total Synthesis of seco-(+)-and ent-(-)-Oxaduocarmycin SA: Construction of the (Chloromethyl)indoline Alkylating Subunit by a Novel Intramolecular Aryl Radical Cyclization onto a Vinyl Chloride. -The seco-(+) title compound (IX) is an analogue of the highly cytotoxic natural product duocarmycin SA,