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Total Synthesis of Macrosphelide M from Diacetone Glucose

โœ Scribed by Gangavaram V. M. Sharma; Post Sai Reddy


Book ID
112082701
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
626 KB
Volume
2012
Category
Article
ISSN
1434-193X

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The total synthesis of macrosphelides A
โœ G.V.M. Sharma; Ch.Chandra Mouli ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 305 KB

Scheme 2. Reagents and conditions: (a) p-TsCl, pyridine, dry CH 2 Cl 2 , 0ยฐC-rt, 14 h; (b) LiAlH 4 , dry THF, 0ยฐC-rt, 18 h; (c) NaH, PMBBr, dry THF, 0ยฐC-rt, 4 h; (d) 60% aq. AcOH, cat. HCl, rt, 14 h; (e) NaIO 4 , MeOH/H 2 O (2:1), rt, 2 h; (f) Ph 3 P CHCOO(CH 2 ) 2 SO 2 Tol, 110ยฐC, 1 h; (g) cat. HCl