𝔖 Bobbio Scriptorium
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Total synthesis of luotonin A

✍ Scribed by T.Ross Kelly; Stephen Chamberland; Richard A. Silva


Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
120 KB
Volume
40
Category
Article
ISSN
0040-4039

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✦ Synopsis


The synthesis of the cytotoxic alkaloid luotonin A (1), which has been shown to possess antileukemic activity, has been achieved. The key step in the synthesis is a Friedl~inder condensation between 2-aminobenzaldehyde and dione 5.


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