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Total Synthesis of Leucascandrolide A

✍ Scribed by Alec Fettes; Erick M. Carreira

Publisher: John Wiley and Sons
Year: 2002
Tongue: English
Weight: 97 KB
Volume: 41
Category: Article
ISSN: 0044-8249
DOI: 10.1002/1521-3773(20021104)41:21<4098::aid-anie4098>3.0.co;2-p

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✍ Alec Fettes; Erick M. Carreira 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 96 KB

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Formal Synthesis of Leucascandrolide A

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Extracts from the calcareous sponge Leucascandra caveolata were collected from waters along the northeastern coast of New Caledonia by Pietra and co-workers, and yielded the novel marine macrolide leucascandrolide A (1). [1] The structure of 1 was elucidated by extensive 2D NMR experiments and analy