Total Synthesis of Halipeptin A: A Potent Antiinflammatory Cyclic Depsipeptide.
โ Scribed by Shouyun Yu; Xianhua Pan; Xianfeng Lin; Dawei Ma
- Publisher
- John Wiley and Sons
- Year
- 2005
- Weight
- 12 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0931-7597
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๐ SIMILAR VOLUMES
The halipeptins A (1) and B (2) are two cyclic depsipeptides that were isolated from the sponge Haliclona species by Gomez-Paloma and co-workers. [1,2] Initially, their structures were misassigned as the 17-membered cyclic depsipeptides containing an unusual oxazetidine. [1] One year later the same
## Abstract Halipeptins AโD (**1โa**โ**d**) are a family of natural cyclic depsipeptides isolated from marine sponges. Total syntheses of these four compounds are detailed in this report. The key elements in this synthesis include the elaboration of the polysubstituted decanoic acid parts by two as