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Total Synthesis of (+)-Geldanamycin and (−)- o -Quinogeldanamycin with Use of Asymmetric Anti- and Syn -Glycolate Aldol Reactions

✍ Scribed by Andrus, Merritt B.; Meredith, Erik L.; Simmons, Bryon L.; Soma Sekhar, B. B. V.; Hicken, Erik J.


Book ID
126054038
Publisher
American Chemical Society
Year
2002
Tongue
English
Weight
93 KB
Volume
4
Category
Article
ISSN
1523-7060

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Asymmetric aldol reactions of chiral Ni(
✍ Vadim A Soloshonok; Dimitry V Avilov; Valery P Kukhar'; Vitali I Tararov; Tatian 📂 Article 📅 1995 🏛 Elsevier Science 🌐 English ⚖ 976 KB

Stereoselectivity of aldol reactions between aliphatic aldehydes and Ni(ll)-complex of chiral non-racemic Schiff base of glycine with (S)-o-[N-(N-benzylprolyl)amino]benzophenone (BPB) in the presence of excess of MeONa, has been studied as a function of time, reaction conditions and nature of an ald