Total synthesis of dl-antibiotic 593A
โ Scribed by Fukuyama, Tohru; Frank, R. Keith; Jewell, Charles F.
- Book ID
- 126172781
- Publisher
- American Chemical Society
- Year
- 1980
- Tongue
- English
- Weight
- 259 KB
- Volume
- 102
- Category
- Article
- ISSN
- 0002-7863
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๐ SIMILAR VOLUMES
Total synthesis of dl-asparenomycins was accomplished with direct conversion of carbonates 13a, 13b and l&, 14b to asparenomycin esters 15 and 16 and carboxy deprotectionby the A1C13-anisole method. --Asparenomycin A A, a broad spectrum antibiotic with potent B-lactamase inhibitory activity, which
Velbanamine wconstitutes the tetmcyclic indole moiety of the dimeric alkaloids, vinblastine wand vincristine &) (l), and wos obtained during structure elucidation studies(lq2)on the latter alkaloids. The reported syntheses of&, a potentiol intermediate for the preparation of the oncolytic alkaloids