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Total synthesis of d,1-mesembrine via regioselective NaBH4-reduction of imides

✍ Scribed by J.B.P.A. Wijnberg; W.N. Speckamp

No coin nor oath required. For personal study only.

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## Abstract The ratio of the formation of nuevamine (IV) and isonuevamine (V) from (III) is strongly dependent on the reducing agent used.