Total synthesis of cyclo-l-rhamnohexaose by a stereoselective thermal glycosylation
โ Scribed by Mugio Nishizawa; Hiroshi Imagawa; Yukiko Kan; Hidetoshi Yamada
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- French
- Weight
- 227 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0040-4039
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๐ SIMILAR VOLUMES
One of the foremest problems encountered in synthesis of diterpenoid resin acids is that of stereoselective introduction of methyl and carboxyl substituents at the quaternary k-position in the correct configuration relative to the C-10 angular methyl. Most previous syntheses
carried out by treating 5 with 1.4-dibromobutane in dimethylformamide (DHF) in the presence of potassium tert-butoxide to afford 6 in 39% yield. Then focus was turned to the synthesis of deoxysesbanine (12). On the contrary to the easy alkoxycarbonylation of 4, treatment of 7 under the same reaction
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