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Total Synthesis of (+)-Aspidospermidine: A New Strategy for the Enantiospecific Synthesis of Aspidosperma Alkaloids

โœ Scribed by Cao, Ganfeng; de Dios, Alfonso; Marino, Joseph P.; Rubio, Maria B.


Book ID
115492519
Publisher
American Chemical Society
Year
2002
Tongue
English
Weight
73 KB
Volume
124
Category
Article
ISSN
0002-7863

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A new strategy for the enantioselective
โœ Didier Desmaele; Jean d'Angelo ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 271 KB

## Carbazolone 5 has been converted in eleven steps into alkaloid analog Z (R = Me) (13 46 overall yield). In the preceding paper l, we proposed a new approach to pentacyclic Aspidosperma alkaloids [(e.g. (-)-aspidospermldine, 1, R = Et], based on the disconnection [l -+ 2 -+ 31, in which carbazol