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Total Synthesis of Angucyclines. Part 18. A Short and Efficient Synthesis of (+)-Ochromycinone.

✍ Scribed by Karsten Krohn; Md. Hossain Sohrab; Ulrich Floerke


Publisher
John Wiley and Sons
Year
2004
Weight
59 KB
Volume
35
Category
Article
ISSN
0931-7597

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πŸ“œ SIMILAR VOLUMES


Total Synthesis of Angucyclines, 4. Synt
✍ Krohn, Karsten ;Khanbabaee, Karamali πŸ“‚ Article πŸ“… 1994 πŸ› John Wiley and Sons 🌐 English βš– 458 KB

## Abstract The synthesis of racemic tetrangomycin (11) is reported. In the key step the hexahydrobenz[Ξ±]anthraquinone 8 is generated in a regioselective Diels‐Alder reaction of diene 5 with bromonaphthoquinone 7. The conversion of 8 into 11 involves only three operations: treatment with diethyl et

Total Synthesis of Angucyclines, 1. – Sy
✍ Krohn, Karsten ;Ballwanz, Frank ;Baltus, Wolfgang πŸ“‚ Article πŸ“… 1993 πŸ› John Wiley and Sons 🌐 English βš– 339 KB

## Abstract The synthesis of the racemic angucyclinone hybrid 3 which combines the structural features of rabelomycin (1) and daunomycinone (2) is described. Key steps are the cyclization of the bromide 6b by a Marshalk‐type reaction to yield the angular skeleton 7b, introduction of the tertiary hy

Total synthesis of angucyclines, 7. Hydr
✍ Krohn, Karsten ;Khanbabaee, Karamali ;Jones, Peter G. πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 English βš– 622 KB

## Abstract Osmylation of the Diels‐Alder adduct 3 afforded the __cis__‐diol 4, which was dehydrated by acid treatment to the phenol 6. Reaction with tetrafluoroboric acid converted the diol 4 by intramolecular acyl shift into the acetate 7. The relative stereochemistry of 7 was determined by singl