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Total Synthesis of an Antitumor Agent, Mucocin, Based on the “Chiron Approach”

✍ Scribed by Takahashi, Shunya; Nakata, Tadashi


Book ID
120251424
Publisher
American Chemical Society
Year
2002
Tongue
English
Weight
236 KB
Volume
67
Category
Article
ISSN
0022-3263

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Total synthesis of an anticancer agent,
✍ Shunya Takahashi; Tadashi Nakata 📂 Article 📅 1999 🏛 Elsevier Science 🌐 French ⚖ 237 KB

The left-half segment of mucocin (1) was stereoselectively synthesized through a coupling reaction of a tetrahydropyranyl aldehyde and a tetrahydrofuran derivative having an ethynyl group, which were prepared from 2, 3,4,6-tetra-O-benzyl-D-galactono-l,5-1actone and 2,5-anhydro-D-mannitol, respective