A ten steps total synthesis of (-) altholactone, enantiomer of an antitumor pyrone isolated from Goniothahw species, is described starting from Dglucose. (+) Altholactone 1 has been isolated in 1977 by LODER et al? from an unknown PotyaZthea species. This substance is characterized by a cis-fused te
Total synthesis of (+) altholactone (goniothalenol) from D-glucose
โ Scribed by Jean-Pierre Gesson; Jean-Claude Jacquesy; Martine Mondon
- Publisher
- Elsevier Science
- Year
- 1987
- Tongue
- French
- Weight
- 195 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0040-4039
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๐ SIMILAR VOLUMES
+tAltholactone 1, an antitumor agent isolated from GoniothaZamus species, has been synthesized starting from L-glyceraldehyde acetonide. (+I-Altholactone 1 from an unknown PoZyathea species has a novel phenyltetrahydrofurano-2pyrone structure rare for natural compounds .I It turned out to be identic
The chiral and stereoselective synthesis of (+)-lactacystin 1, the first non-protein neurotrophic factor having an ct,~t-disubstituted a-amino acid structure, is described. The highly functionalized y-lactam portion possessing a tetra-substituted carbon with nitrogen in I was effectively constructed