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Total synthesis of 8-iso 19-nor testosterone and 8-iso 10-iso 19-nor testosterone

โœ Scribed by R. Bucourt; D. Hainaut; J.-C. Gasc; G. Nomine


Publisher
Elsevier Science
Year
1969
Tongue
French
Weight
27 KB
Volume
10
Category
Article
ISSN
0040-4039

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## Abstract Cationic cyclization of 2โ€[6โ€(3โ€methoxyphenyl)โ€(Z)โ€3โ€hexenyl]โ€3โ€methylโ€2โ€cyclopentenol (7a) produced 1โ€ and 3โ€methoxyโ€17โ€methylโ€8ฮฑโ€gonaโ€1,3,5(10),13(17)โ€tetraene (**8a** and **9a**) with complete stereospecificity. Cyclization of similar substrates with an alkyl substituent in the appro