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Total synthesis and properties of prostaglandins 30. Modification of (1S,5R)-2-oxabicyclo[3.3.0]-6-octen-3-one at theα-carbon atom

✍ Scribed by K. I. Dikovskaya; T. V. Mazur; I. V. Turovskii; M. P. Gavars; Ya. F. Freimanis


Book ID
104790017
Publisher
Springer US
Year
1991
Tongue
English
Weight
766 KB
Volume
27
Category
Article
ISSN
0009-3122

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Enzymes in Organic Synthesis, 8. Synthes
✍ Weidner, Judith ;Theil, Fritz ;Kunath, Annamarie ;Schick, Hans 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 271 KB

## Abstract Lipase Amano PS is a suitable biocatalyst for the highly regio‐ and enantioselective transesterification of the racemic prostaglandin building block (1__S__~\*~,5__R__\*,6__R__\*,7__R__\*)‐(±)‐7‐hydroxy‐6‐hydroxymethyl‐2‐oxabicyclo[3.3.0]octan‐3‐one (__rac__‐1) yielding (1__S__,5__R__,6