Total syntheses of (+)-monomorine I and (−)-indolizidine 195B from sulfinimine-derived 3-oxo pyrrolidine 2-phosphonates

✍ Scribed by Franklin A. Davis; Junyi Zhang; Yongzhong Wu

• Book ID: 104098481
• Publisher: Elsevier Science
• Year: 2011
• Tongue: French
• Weight: 355 KB
• Volume: 52
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/j.tetlet.2010.10.076

✦ Synopsis

Indolizidine alkaloids (+)-monomorine I (1) and (À)-indolizidine 195B (2), having cis and trans relationships of the C-3 and C-9 substituents, respectively, were prepared from the sulfinimine-derived chiral building blocks N-sulfinyl d-amino b-ketophosphonate and 3-oxo pyrrolidine 2-phosphonate.