Total Syntheses of Isomeric Spiroacetal Marine Natural Products Attenols A and B
β Scribed by Kumar, Vemula Praveen; Kavitha, Nerella; Chandrasekhar, Srivari
- Book ID
- 120648305
- Publisher
- John Wiley and Sons
- Year
- 2013
- Tongue
- English
- Weight
- 767 KB
- Volume
- 2013
- Category
- Article
- ISSN
- 1434-193X
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## Abstract The bengazoles are a family of marine natural products that display potent antifungal activity and a unique structure, containing two oxazole rings flanking a single carbon atom. Total syntheses of bengazole A and B are described, which contain a sensitive stereogenic centre at this pos
Natural (+)-sesbanimide A (l) and (-)-sesbanimide B ($, potent antitumor alkaloids, were efficiently synthesized from the (-)-glutarimide diol ($, corresponding to the AB-ring system of l and &, which had already been derived from readily available D-xylose. Our total synthesis obviously established