Total Intravenous Anesthesia and Target Controlled Infusions: A Comprehensive Global Anthology

✍ Scribed by Anthony R. Absalom, Keira P. Mason (eds.)

• Publisher: Springer International Publishing
• Year: 2017
• Tongue: English
• Leaves: 813
• Edition: 1
• Category: Library

✦ Synopsis

This is a comprehensive and authoritative presentation of total intravenous anesthesia (TIVA) and target controlled infusion (TCI). The editors’ international reputation has enabled them to recruit leading experts from around the world to write single-author chapters in their area of expertise. Total Intravenous Anesthesia and Target Controlled Infusions is the first multi-disciplinary, globally authored volume on the topic.
Providing a single source of information on all aspects of TIVA and TCI, from pharmacologic modeling and the pharmacology of intravenous anesthetic drugs to practical considerations in the clinical setting and the requirements of special populations, Total Intravenous Anesthesia and Target Controlled Infusions examines the debate about the risks and advantages of TIVA, analyze outcome studies, and provides guidance on creating a curriculum to teach TIVA and TCI.

✦ Table of Contents

Front Matter....Pages i-xviii
Front Matter....Pages 1-1
When and How Did It All Begin? A Brief History of Intravenous Anesthesia....Pages 3-8
The Development and Regulation of Commercial Devices for Target-Controlled Drug Infusion....Pages 9-29
The Memory Labyrinth: Systems, Processes, and Boundaries....Pages 31-62
Consciousness and Anesthesia....Pages 63-78
Mechanisms of Intravenous Anesthetic Action....Pages 79-95
Front Matter....Pages 97-97
Basic Pharmacology: Kinetics and Dynamics for Dummies....Pages 99-116
Pharmacokinetic–Pharmacodynamic Modelling of Anesthetic Drugs....Pages 117-145
Principles of Target-Controlled Infusions....Pages 147-157
Performance of Target-Controlled Infusion Systems....Pages 159-170
How to Select a PK/PD Model....Pages 171-187
Front Matter....Pages 189-189
Propofol PK-PD....Pages 191-208
Etomidate and Etomidate Analogues: Molecular Pharmacology and Behavioral Actions....Pages 209-219
Dexmedetomidine: The Science and Clinical Aspects in Adults and Children....Pages 221-244
Clinical Effects and Applications of Ketamine....Pages 245-265
Neuromuscular Blocking Drugs: Physiology, Pharmacology and Clinical Aspects....Pages 267-297
New and Upcoming Drugs: Intravenous Anesthetic Agents....Pages 299-312
Drug Interactions in Anesthesia....Pages 313-325
Front Matter....Pages 327-327
Pump Pitfalls and Practicalities....Pages 329-340
EEG Monitoring of Depth of Anesthesia....Pages 341-356
Monitoring the Analgesic Component of Anesthesia....Pages 357-368
Front Matter....Pages 327-327
Intravenous Drugs for Sedation: Target-Controlled, Patient-Controlled and Patient-Maintained Delivery....Pages 369-390
Pediatric TIVA/TCI: Case Presentations and Discussion....Pages 391-401
TCI/TIVA Adult Case Studies....Pages 403-425
Front Matter....Pages 427-427
Intravenous Anesthesia in Obese Patients....Pages 429-440
Pharmacokinetics and Pharmacodynamics in the Pediatric Patient....Pages 441-516
Clinical Pharmacology of Intravenous Sedation in Children....Pages 517-535
Sedation of the Critically Ill Child....Pages 537-560
TCI and TIVA for Neurosurgery: Considerations and Techniques....Pages 561-569
TCI in Special Patients Groups: The Elderly and Obese....Pages 571-578
TIVA for Cardiac Surgery....Pages 579-588
TIVA/TCI in Veterinary Practice....Pages 589-618
Front Matter....Pages 619-619
Advantages, Disadvantages, and Risks of TIVA/TCI....Pages 621-631
Economics of TIVA....Pages 633-638
Teaching TCI with Human Patient Simulators....Pages 639-648
Closed-Loop or Automated Titration of Intravenous Anesthesia: Background, Science, and Clinical Impact....Pages 649-666
Health Care Technology, the Human–Machine Interface, and Patient Safety During Intravenous Anesthesia....Pages 667-683
Can IV Sedatives Affect Outcome?....Pages 685-696
The Benefit and Future of Pharmacogenetics....Pages 697-711
Lessons From Drug Interaction Displays....Pages 713-723
The Role of Intravenous Agents in Delirium....Pages 725-748
Front Matter....Pages 619-619
Perioperative Cardioprotective Strategies in Noncardiac Surgery....Pages 749-761
Opioid-Induced Hyperalgesia After Surgery: Clinical Relevance....Pages 763-773
Memory, Awareness and Intravenous Anesthetics....Pages 775-782
Awareness and Dreaming During TIVA....Pages 783-796
Apoptosis and Neurocognitive Effects of IV Anesthetics....Pages 797-803
Back Matter....Pages 805-824

✦ Subjects

Anesthesiology;Traumatic Surgery