Pharmacokinetics of total and free valpr
✍
L. Herngren; B. Lundberg; A. Nerg»rdh
📂
Article
📅
1991
🏛
Springer
🌐
English
⚖ 421 KB
The pharmacokinetics of free and total valproic acid (VPA) in plasma and whole blood after oral administration during steady state was investigated in seven infants (mean age 10.7 months) receiving monotherapy. The VPA concentrations in whole blood closely followed those in plasma but at a reduced l