𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Topotecan for the Treatment of Recurrent or Progressive Central Nervous System Tumors – A Pediatric Oncology Group Phase II Study

✍ Scribed by Richard P. Kadota; Clinton F. Stewart; Marianna Horn; John F. Kuttesch; Peter C. Burger; James L. Kepner; Larry E. Kun; Henry S. Friedman; Richard L. Heideman


Book ID
110233964
Publisher
Springer US
Year
1999
Tongue
English
Weight
31 KB
Volume
43
Category
Article
ISSN
0167-594X

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Ifosfamide/etoposide combination in the
✍ Faith H. Kung; Charles B. Pratt; Roger A. Vega; Norman Jaffe; Douglas Strother; 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 509 KB

Background. The prognosis for children with recurrent or resistant malignant solid tumors remains dismal. More effective rescue therapy is needed for these children. Methods. Between August 1987 and November 1990, 311 children with recurrent or resistant malignant solid tumors were treated by inves

A phase II study of homoharringtonine fo
✍ Bell, Beverly A. ;Chang, Myron N. ;Weinstein, Howard J. 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 106 KB

## Abstract ## Background Homoharringtonine (HHT) is a plant alkaloid that is derived from a Chinese evergreen tree. Its mechanism of action is thought to be by inhibition of protein, DNA, and RNA synthesis by inhibition of chain initiation. The treatment of acute myelogenous leukemia (AML) in chi

Oral topotecan in children with recurren
✍ Sabine Wagner; Bernhard Erdlenbruch; Alfred Längler; Astrid Gnekow; Joachim Kühl 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 165 KB 👁 1 views

## Abstract ## BACKGROUND Continuous oral treatment with topotecan may be more effective than the typical 1‐day and 5‐day treatment schedules. In previous studies of continuous treatment with topotecan, increased intestinal side effects were reported in adult patients; however, the experience in p

Phase 2 study of temozolomide in childre
✍ H. Stacy Nicholson; Cynthia S. Kretschmar; Mark Krailo; Mark Bernstein; Richard 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 107 KB 👁 1 views

## Abstract ## BACKGROUND. Effective chemotherapy is lacking for most types of central nervous system (CNS) tumors in children. Temozolomide, an agent with activity against adult brain tumors, was investigated in children and adolescents with recurrent CNS tumors. ## METHODS. Temozolomide was ad