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Topological aspects of conformational transformations in proteins

✍ Scribed by S. Chiavarini; P. De Santis; S. Morosetti; A. Palleschi

Publisher: Wiley (John Wiley & Sons)
Year: 1984
Tongue: English
Weight: 656 KB
Volume: 23
Category: Article
ISSN: 0006-3525
DOI: 10.1002/bip.360230810

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✦ Synopsis

The topological aspects of the conformational transformations in proteins are investigated using a new peptide-ribbon representation of the tertiary structure. The topological parameters evaluated on a set of 49 proteins show striking regularities that extend beyond the secondary structures actually present and are interpreted as a manifestation of the topological invariance of conformational transformations in globular proteins.

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