Topoisomerase IIโฃ (TOP2A) is a key enzyme in DNA replication and a molecular target for many important anticancer drugs. TOP2A is amplified or deleted together with amplification of the closely located ERBB2/HER-2/neu oncogene in breast cancer. We characterized the copy number aberrations of TOP2A a
โฆ LIBER โฆ
Topoisomerase II-alpha gene deletion is not frequent as its amplification in breast cancer
โ Scribed by Kyeongmee Park; Sehwan Han; Geum-Hee Gwak; Huyn-jung Kim; Jungyeon Kim; Kyoung-Mee Kim
- Book ID
- 106377071
- Publisher
- Springer US
- Year
- 2006
- Tongue
- English
- Weight
- 202 KB
- Volume
- 98
- Category
- Article
- ISSN
- 0167-6806
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