Topographic patterns of odorant receptor expression in mammals: a comparative study
โ Scribed by J. Strotmann; A. Beck; S. Kubick; H. Breer
- Book ID
- 104655951
- Publisher
- Springer
- Year
- 1995
- Tongue
- English
- Weight
- 885 KB
- Volume
- 177
- Category
- Article
- ISSN
- 0340-7594
No coin nor oath required. For personal study only.
โฆ Synopsis
In a comparative study, molecular probes for various odorant receptor subtypes were employed in in situ hybridization experiments on tissue sections through the nose from different mammalian species. OR37 reactive neurons were found exclusively in the rodent species, where they were clustered in very similar position within the nasal cavities; an OR37-related receptor subtype was not detectable in the rabbit. All other subtypes tested, hybridized across species borders to neurons that were distributed within distinct zones of the olfactory epithelium. Most receptor types were found in the same zone in all species; however, a few subtypes which are expressed in the medial zone in rat were found in the dorsal zone in guinea pig.
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