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Topographic patterns of odorant receptor expression in mammals: a comparative study

โœ Scribed by J. Strotmann; A. Beck; S. Kubick; H. Breer


Book ID
104655951
Publisher
Springer
Year
1995
Tongue
English
Weight
885 KB
Volume
177
Category
Article
ISSN
0340-7594

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โœฆ Synopsis


In a comparative study, molecular probes for various odorant receptor subtypes were employed in in situ hybridization experiments on tissue sections through the nose from different mammalian species. OR37 reactive neurons were found exclusively in the rodent species, where they were clustered in very similar position within the nasal cavities; an OR37-related receptor subtype was not detectable in the rabbit. All other subtypes tested, hybridized across species borders to neurons that were distributed within distinct zones of the olfactory epithelium. Most receptor types were found in the same zone in all species; however, a few subtypes which are expressed in the medial zone in rat were found in the dorsal zone in guinea pig.


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