𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Topochemical models for the prediction of poly(ADP-ribose) polymerase inhibitory activity of indole-1-ones

✍ Scribed by Harish Dureja; A. K. Madan


Publisher
Springer-Verlag
Year
2007
Tongue
English
Weight
358 KB
Volume
16
Category
Article
ISSN
1054-2523

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Binding kinetics and activity of human p
✍ Timothy J. Jorgensen; Kevin Chen; Sergey Chasovskikh; Rabindra Roy; Anatoly Drit πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 314 KB

## Abstract Poly(ADP‐ribose) polymerase‐1 (PARP‐1) is a mammalian enzyme that attaches long branching chains of ADP‐ribose to specific nuclear proteins, including itself. Because its activity __in vitro__ is dependent upon interaction with broken DNA, it has been postulated that PARP‐1 plays an imp

Effect of poly(ADP-ribose) polymerase 1
✍ Liudmila G. Romanova; Jeana Zacharias; Mark L. Cannon; Nicola J. Philpott πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 307 KB

## Abstract ## Background Adeno‐associated virus type 2 (AAV) has the ability to target integration of its DNA into a specific locus of the human genome. Site‐specific AAV integration is mediated by viral Rep proteins, although the role of cellular factors involved in this process is largely unkno