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Topical application of the immunosuppressant tacrolimus accelerates carcinogenesis in mouse skin

✍ Scribed by Y. Niwa; T. Terashima; H. Sumi


Book ID
108667375
Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
269 KB
Volume
149
Category
Article
ISSN
0007-0963

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## Abstract Peroxisome proliferator‐activated receptor Ξ³ (PPARΞ³) is a ligand activated transcription factor. There have been suggestions that PPARΞ³ ligands may have utility in preventing tumor development in rodent mammary glands and colon. The recent finding that mice lacking one allele of the __P