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Tonotopy in human auditory cortex examined with functional magnetic resonance imaging

โœ Scribed by C. Mark Wessinger; Michael H. Buonocore; Clif L. Kussmaul; George R. Mangun


Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
205 KB
Volume
5
Category
Article
ISSN
1065-9471

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โœฆ Synopsis


Tonotopic organization within the human auditory cortex was investigated with functional magnetic resonance imaging (fMRI) using the blood oxygenation level-dependent (BOLD) contrast mechanism. Single-frequency pulsed tones were alternated with no-tone conditions to elicit stimulusspecific functional activity. Differential frequency-specific activity was imaged within the auditory cortex Activations for high-frequency tones were located more posteriorly and medially than those for low-frequency tones. Such a pattern is consistent with descriptions of tonotopic organization suggested by other nonneuroimaging methodologies used with human and nonhuman primates. Furthermore, these results demonstrate that fMRI can be used to reliably investigate functional organization of the human auditory cortex. Hum.


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