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Toluene-induced, Ca2+-dependent vesicular catecholamine release in rat PC12 cells

✍ Scribed by Remco H.S. Westerink; Henk P.M. Vijverberg


Book ID
117472774
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
109 KB
Volume
326
Category
Article
ISSN
0304-3940

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The membrane electrical properties of undifferentiated pheochromocytoma cells of the rat (PC12) were studied using both current-and voltage-clamp techniques with the use of low-resistance blunt-tipped micropipettes (patch electrodes). In the presence of tetrodotoxin (TTX, 2-3 ~tM), a spike-like wave