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Toll-like receptors: mammalian ‘taste receptors’ for a smorgasbord of microbial invaders

✍ Scribed by Peter A Sieling; Robert L Modlin

Book ID
117764852
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
88 KB
Volume
5
Category
Article
ISSN
1369-5274

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The generation of cell-mediated immunity against many infectious pathogens involves the production of interleukin-12 (IL-12), a key signal of the innate immune system. Yet, for many pathogens, the molecules that induce IL-12 production by macrophages and the mechanisms by which they do so remain und