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Toll-like receptors: critical proteins linking innate and acquired immunity

✍ Scribed by Akira, Shizuo; Takeda, Kiyoshi; Kaisho, Tsuneyasu

Book ID
109831996
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
406 KB
Volume
2
Category
Article
ISSN
1529-2908

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Innate immunity represents the first line of defense against invading pathogens and noxious stimuli. The Toll-like receptors (TLRs) are essential innate immune receptors that alert the immune system to the presence of invading microbes. Emerging evidence shows that TLR signaling is important in allo