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Toll-like receptors as an escape mechanism from the host defense

โœ Scribed by Mihai G. Netea; Jos W.M. Van der Meer; Bart-Jan Kullberg

Book ID
116917081
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
266 KB
Volume
12
Category
Article
ISSN
0966-842X

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The generation of cell-mediated immunity against many infectious pathogens involves the production of interleukin-12 (IL-12), a key signal of the innate immune system. Yet, for many pathogens, the molecules that induce IL-12 production by macrophages and the mechanisms by which they do so remain und