Toll-like receptors and their adapter molecules
β Scribed by A. I. Tukhvatulin; D. Yu. Logunov; D. N. Shcherbinin; M. M. Shmarov; B. S. Naroditsky; A. V. Gudkov; A. L. Gintsburg
- Book ID
- 110155438
- Publisher
- Springer
- Year
- 2010
- Tongue
- English
- Weight
- 357 KB
- Volume
- 75
- Category
- Article
- ISSN
- 0006-2979
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Toll-like receptors (TLRs) are pattern recognition receptors that recognize pathogen-associated molecular patterns and signal through adaptor molecules, myeloid differentiation factor 88 (MyD88), Toll/IL-1 receptor domain containing adaptor protein (TIRAP), Toll/IL-1 receptor domain containing adapt
## Abstract Toll like receptors (TLRs) are βpattern recognition proteinsβ that discriminate between self and nonβself. They interact with products of infectious agents to activate cells of the innate immune system and also stimulate the adaptive immune system. Intracellular and extracellular TLRs r