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Toll-like receptor (TLR)2 and TLR3 synergy and cross-inhibition in murine myeloid dendritic cells

✍ Scribed by François Vanhoutte; Christophe Paget; Laetitia Breuilh; Josette Fontaine; Catherine Vendeville; Stanislas Goriely; Bernhard Ryffel; Chistelle Faveeuw; François Trottein

Book ID: 108152352
Publisher: Elsevier Science
Year: 2008
Tongue: English
Weight: 583 KB
Volume: 116
Category: Article
ISSN: 0165-2478
DOI: 10.1016/j.imlet.2007.11.014

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## Abstract Severe injury deranges immune function and increases the risk of sepsis and multiple organ failure. Kupffer cells play a major role in mediating posttraumatic immune responses, in part via different Toll‐like receptors (TLR). Although mitogen‐activated protein kinases (MAPK) are key ele