## Abstract ## Background Triptolide is a diterpene triepoxide from the Chinese medicinal plant __Tripterygium wilfordii__ Hook F., with known anti-inflammatory, immunosuppressive and anti-cancer properties. ## Results Here we report the expression profile of immune signaling genes modulated by
โฆ LIBER โฆ
Toll-like receptor-mediated tyrosine phosphorylation of paxillin via MyD88-dependent and -independent pathways
โ Scribed by Kaoru Hazeki; Naoyo Masuda; Kenji Funami; Naoe Sukenobu; Misako Matsumoto; Shizuo Akira; Kiyoshi Takeda; Tsukasa Seya; Osamu Hazeki
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 199 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0014-2980
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IL-3-dependent mucosal-like mast cells undergo apoptosis upon withdrawal of IL-3. Generally, the apoptosis is mediated by the activation of caspases and inhibited by addition of the pan-caspase inhibitors z-VAD-FMK or BOC-D-FMK. However, DNA fragmentation, a typical characteristic of apoptosis, is n