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Toll-like receptor expression in smokers with and without COPD

✍ Scribed by Ida von Scheele; Kjell Larsson; Barbro Dahlén; Bo Billing; Maria Skedinger; Ann-Sofie Lantz; Lena Palmberg

Book ID: 116872994
Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 728 KB
Volume: 105
Category: Article
ISSN: 0954-6111
DOI: 10.1016/j.rmed.2011.02.012

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## Abstract Toll‐like receptors comprise a family of evolutionary conserved pattern recognition receptors that act as a first defense line in the innate immune system. Upon stimulation with microbial ligands, they orchestrate the induction of a host defense response by activating different signalin