The role of MAPK in Kupffer cell toll-li
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Bjoern M. Thobe; Michael Frink; Frank Hildebrand; Martin G. Schwacha; William J.
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Article
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2006
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John Wiley and Sons
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English
β 209 KB
## Abstract Severe injury deranges immune function and increases the risk of sepsis and multiple organ failure. Kupffer cells play a major role in mediating posttraumatic immune responses, in part via different Tollβlike receptors (TLR). Although mitogenβactivated protein kinases (MAPK) are key ele