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Toll-like receptor 4 mediates ischemia/reperfusion injury of the heart

✍ Scribed by Albert J. Chong; Akira Shimamoto; Craig R. Hampton; Hiroo Takayama; Denise J. Spring; Christine L. Rothnie; Masaki Yada; Timothy H. Pohlman; Edward D. Verrier


Book ID
113759386
Publisher
CTSNet
Year
2004
Tongue
English
Weight
492 KB
Volume
128
Category
Article
ISSN
1097-685X

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Toll-like receptor 4 is a key mediator o
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Steatotic donors are routinely rejected for transplantation because of their increased rate of primary nonfunction. These grafts are more sensitive to ischemia/reperfusion (I/R) during transplantation. Removal of endotoxin before reperfusion improves liver performance post-I/R. We hypothesize that t